Thursday, June 14, 2012

Caffeine and Nitric Oxide: Approaching Pseudo-Steroids-

As Filippo Carlucci was introducing what we were going to be analyzing in his lab, he mentioned a few of the multiple uses of caffeine, some of which he seemed to be quite knowledgeable about.  Although recognizable by others in the group, I had never heard of caffeine being used for sport-enhancement purposes.  Although caffeine primarily influences strength endurance, I have heard of a similar technique from back in the states for improving athletic power, supplementing a workout with nitric oxide.

Nitric Oxide
Caffeine



Caffeine is a widely known stimulant of the methylxanthine family that is naturally found in over 60 plant species.  It also labeled as a psychoactive drug, but unlike other psychoactive drugs, caffeine is both legal and unregulated in almost all parts of the world.  Over the years, caffeine use has become widespread, to the point where it is the most inexpensive and widely available drug in the world.  Many adults consume caffeine daily, mostly for that morning-wake-up feeling that’s like being hit by a train for anyone not enjoying morning coffee.  For athletes, the story is a little different.

In sport performance, caffeine can improve the endurance of athletes and enhance concentration.  Filippo mentioned that some athletes consume 12-18 caffeine pills each containing 50 mg about 2 hours before their competition to obtain the greatest benefits from the caffeine.  For those in sports such as running and soccer, caffeine increases physical endurance, allowing athletes to improve their strength and feel less exhausted.  It has been tested that for athletes who require short bursts of energy (such as sprinters and swimmers), taking caffeine to improve performance has little effect.  For sports requiring the athlete to maintain focus and remain calm (such as fencing), caffeine stimulates the central nervous system causing heightened reactions and increased concentration.  This is due to the fact that caffeine can slow substances that stop neuronal firing.  In regard to increased strength, caffeine can transfer calcium, sodium, and potassium into cells.  This transfer increases membrane permeability, which in turn allows for more powerful muscle contractions.

In America, I have never heard of athletes using caffeine.  I have heard of nitric oxide though.  At a suggestion from a friend, I almost took nitric oxide once.  After researching a little, I passed, as I was unsure of all the side effects.  Nitric oxide (NO), or nitrogen monoxide, is a free radical that functions in the body’s vascular system.  It is produced from the amino acid L-arginine (the main ingredient in supplements) by the enzyme activity of nitric oxide synthase in endothelial cells.  The nitric oxide is released into the blood vessels of muscles, causing the vessels to relax, creating an opportunity for more blood to flow through the muscles giving the athlete a bigger “pump” feeling.  This enlargement of the blood vessels also provides for quicker recovery, enhanced muscle gain, greater strength, and more endurance.

Both caffeine and nitric oxide provide ergogenic aid to athletes who use these methods for sport-performance or muscle gain enhancements.  Caffeine mainly deals with augmenting athletes for the day of a competition, while nitric oxide provides a more long-term supplement.  For my daily routine, I prefer not to add large quantities of caffeine to my diet and try to avoid supplements such as nitric oxide of which I’m not completely convinced of the side effects.

References:
And Filippo Carlucci’s work

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